
Revolutionizing Antivenom: The Quest to Neutralize Snake Venom with De Novo AI Designed Proteins
Snakebite envenoming poses a persistent threat to public health. The World Health Organization recognizes it as a neglected tropical disease, responsible for over 100,000 deaths annually and leaving another 300,000 individuals with permanent disabilities.In groundbreaking research, scientists have turned to de novo designed proteins as a novel approach to counteract these venom toxins. Using deep learning methods, researchers have successfully created protein designs that demonstrate potential as next-generation antivenom therapeutics.
Targeting Cellular Senescence: A New Frontier in Combating Cancer and Age-Related Diseases
In the realm of cellular biology, senescence has emerged as a pivotal process influencing both the progression of cancer and the onset of age-related diseases. Defined as a state where cells cease to divide but remain metabolically active, senescence acts as a double-edged sword. Key life sciences companies are pinning pipeline hopes in cracking this.
Hydroclimate Volatility: Navigating Extremes on a Warming Earth
In the face of a rapidly changing climate, the concept of hydroclimate volatility has emerged as a critical area of study, highlighting the dramatic and often sudden fluctuations between extremely dry and wet conditions. This phenomenon poses significant challenges to both natural ecosystems and human societies
Dear World Leaders, A Clarion Call to Action: Addressing the Peril of Antarctic Sea Ice Loss
We write to you today with a profound sense of alarm and a pressing need for urgent action. The events unfolding in the Antarctic are a stark harbinger of the dangers posed by climate change, and they demand an immediate and concerted global response.
征服连接组绘制大脑的秘密
Seung 和 Murthy 利用电子显微镜拍摄的苍蝇大脑切片图像,开发 FlyWire 地图已有四年多时间。在人工智能(AI)工具的帮助下,研究人员及其数百名全球同事将数据拼接在一起,形成了完整的大脑地图。这是一项巨大的成就,已经在该领域掀起了一场革命。
稳定性 Oracle:设计稳定蛋白质的强大工具
在飞速发展的生物技术领域,能否设计出稳定性更强的蛋白质是一项严峻的挑战。能够准确预测氨基酸突变将如何影响蛋白质热力学稳定性的计算方法将彻底改变蛋白质工程过程。 Stability Oracle 是一种新的深度学习框架,在预测热力学稳定蛋白质突变方面优于最先进的方法。
埋藏的宝藏:火星粘土如何揭开地球神秘的过去
早期的火星大气层曾经充满二氧化碳,但随着时间的推移,这种浓厚的大气层急剧变薄。这些碳都去哪儿了呢?答案可能就在覆盖在火星表面的岩石和矿物中
将木质素转化为喷气燃料:可持续的航空突破
随着全球航空业努力减少对环境的影响,开发可替代传统石油喷气燃料的可持续航空燃料(SAF)的竞赛也在进行。一个前景广阔的解决方案来自一个不太可能的来源--丰富的生物聚合物木质素
智取真菌入侵者病原体如何劫持我们的免疫防御系统
真菌对人类健康的主要威胁常常被忽视,而细菌和病毒感染所造成的巨大影响则使其黯然失色。然而,这些真核微生物却构成了日益严重的威胁,每年造成全球数百万人死亡。而它们的成功在很大程度上是因为它们有能力操纵我们赖以保持健康的免疫防御系统。
为干旱世界解渴:紧凑型燃料动力大气集水器
随着全球人口的不断激增和气候变化对传统水源的破坏,对淡水生产创新方法的需求从未像现在这样迫切。现在,一种前景广阔的解决方案已经出现,那就是基于吸附技术的大气集水(SAWH)装置
哮喘的单一疗法:设计具有多种靶向能力的长效 T 细胞
北京清华大学的研究人员可能已经找到了一种替代方法,只需一次治疗就能使严重哮喘长期缓解:工程长寿命 T 细胞具有同时针对多种哮喘驱动因素的独特能力。

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A recent study has unraveled some of the secrets concealed within the entangled web of quantum systems.
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Researchers found a strategy to create catalysts that make the production of hydrogen for clean fuel more efficient and affordable.
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A recent global survey of 156 institutions reveals strong interest in VR-haptic technology for dental training, yet significant barriers impede widespread adoption.
天文学家在距离地球仅 2000 光年的银河系中发现了一个巨大的恒星黑洞。这个黑洞是 "偶然 "从欧洲航天局盖亚任务收集的数据中发现的。这个黑洞被命名为盖亚 BH3,简称 BH3。它是目前已知的距离地球第二近的黑洞。在盖亚天体测量中发现一个休眠的33太阳质量黑洞。天文学与天体物理学》,2024;DOI:10.1051/0004-6361/202449763
标题横幅:2012 年 7 月 4 日,欧洲核子研究中心大型强子对撞机的 ATLAS 和 CMS 实验宣布,它们分别在 126 GeV 左右的质量区域观测到了一种新粒子。这种粒子与标准模型预测的希格斯玻色子一致。标准模型中提出的希格斯玻色子是布劳特-恩格勒特-希格斯机制最简单的表现形式。其他类型的希格斯玻色子是由标准模型之外的其他理论预测的。2013 年 10 月 8 日,诺贝尔物理学奖(外部链接)联合授予弗朗索瓦-恩格勒特和彼得-希格斯,"以表彰他们在理论上发现了一种机制,该机制有助于我们理解亚原子粒子质量的起源,最近,欧洲核子研究中心大型强子对撞机的 ATLAS 和 CMS 实验发现了所预测的基本粒子,从而证实了这一机制"。DarkDrug 的徽标显示的是银河系,这是我们称之为家的星系,但我们只探索了其中的一小部分。