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"医学是恢复不和谐的元素;疾病是注入活体的元素的不和谐"。- 达芬奇

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Targeting Cellular Senescence: A New Frontier in Combating Cancer and Age-Related Diseases

Targeting Cellular Senescence: A New Frontier in Combating Cancer and Age-Related Diseases

In the realm of cellular biology, senescence has emerged as a pivotal process influencing both the progression of cancer and the onset of age-related diseases. Defined as a state where cells cease to divide but remain metabolically active, senescence acts as a double-edged sword. Key life sciences companies are pinning pipeline hopes in cracking this.

PharmaScience
Targeting Cellular Senescence: A New Frontier in Combating Cancer and Age-Related Diseases

Targeting Cellular Senescence: A New Frontier in Combating Cancer and Age-Related Diseases

In the realm of cellular biology, senescence has emerged as a pivotal process influencing both the progression of cancer and the onset of age-related diseases. Defined as a state where cells cease to divide but remain metabolically active, senescence acts as a double-edged sword. Key life sciences companies are pinning pipeline hopes in cracking this.

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Navigating the New Frontier: The First Abridged Complaint under the 2024 ABPI Code

Navigating the New Frontier: The First Abridged Complaint under the 2024 ABPI Code

In the ever-evolving landscape of pharmaceutical marketing, the industry faces a delicate balance between informing the public and adhering to strict regulations. This challenge was thrust into the spotlight with the recent case of CSL Seqirus and the alleged promotion of their prescription-only Flucelvax Influenza vaccine on the social media platform LinkedIn.

人工智能制药科学
稳定性 Oracle:设计稳定蛋白质的强大工具

稳定性 Oracle:设计稳定蛋白质的强大工具

在飞速发展的生物技术领域,能否设计出稳定性更强的蛋白质是一项严峻的挑战。能够准确预测氨基酸突变将如何影响蛋白质热力学稳定性的计算方法将彻底改变蛋白质工程过程。 Stability Oracle 是一种新的深度学习框架,在预测热力学稳定蛋白质突变方面优于最先进的方法。

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英国的未来药方?

英国的未来药方?

生命科学行业目前正面临着日益加剧的全球竞争,其他国家都在积极争取该行业的宝贵资产和专业知识。与此同时,国家医疗服务系统(NHS)也在努力应对预算紧张和更新、更创新的药物成本上升的双重挑战。

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CAR T 细胞的前景:癌症免疫疗法的进展与挑战

CAR T 细胞的前景:癌症免疫疗法的进展与挑战

自首次临床试验开始以来的十多年间,长期随访数据证实 CAR T 细胞能够诱导某些患者获得持久缓解。然而,这种疗法也面临着挑战,因为并非所有接受治疗的癌症都有同样好的反应,而且毒性仍然是一个令人担忧的问题。正在进行的研究旨在优化 CAR T 细胞治疗的各个方面,以在更大范围内改善疗效。

  • Solar and electric-powered homes feel the effects...
    on February, 2025 at 11:19 pm

    An expert in energy technologies uses AI tools to investigate the impact of extreme weather on solar-powered and electrified homes and uncover their unique vulnerabilities and develop insights on how they handle harsh conditions.

  • Personalized cancer treatment using 3D...
    on February, 2025 at 5:27 pm

    Scientists have successfully developed a gastric cancer model using 3D bioprinting technology and patient-derived cancer tissue fragments. This innovative model preserves the characteristics of actual patient tissues and is expected to rapidly evaluate and predict individual patient drug responses.

  • Temperamental stars are distorting our view of...
    on February, 2025 at 5:24 pm

    'Temperamental' stars that brighten and dim over a matter of hours or days may be distorting our view of thousands of distant planets, suggests a new study.

  • Researchers achieve total synthesis of ibogaine
    on February, 2025 at 3:39 am

    Researchers have achieved total chemical synthesis of the psychoactive compound ibogaine and its analogs from pyridine. The discovery will make it easier to explore the therapeutic possibilities of ibogaine.

  • Multinational research project shows how life on...
    on February, 2025 at 9:47 pm

    Measurements and data collected from space can be used to better understand life on Earth. An ambitious, multinational research project has demonstrated that Earth's biodiversity can be monitored and measured from space, leading to a better understanding of terrestrial and aquatic ecosystems.

BBC 虚拟现实罗马

该网站现已关闭,我们正在疯狂地寻找类似的体验!

哈勃组织

自 1990 年 4 月 24 日搭乘发现号航天飞机发射升空以来,哈勃揭示了人类历史上大部分时间里只有科学家和哲学家才能探究的空间和时间特性。 

科学感

Sense about Science 是一家独立的慈善机构,致力于促进公众对可靠科学和证据的关注。Sense about Science 成立于 2002 年,与决策者、世界领先的研究人员和社区团体合作,共同提高公共生活中的证据标准。

钱德拉天文台

自 1999 年 7 月 23 日发射以来,钱德拉 X 射线天文台一直是 NASA X 射线天文学的旗舰任务,在 "伟大天文台 "舰队中占有一席之地。

世界自然保护联盟红色名录

国际自然保护联盟的《濒危物种红色名录》于 1964 年制定,现已发展成为世界上最全面的关于全球动物、真菌和植物物种灭绝风险状况的信息来源。

斯科特-哈特曼的骨骼图画

斯科特-哈特曼(Scott Hartman)细致严谨的骨骼重建工作为长脚类动物树立了标准:他现在已经成为人们寻找精确、解剖正确的作品时的首选。

11 年后,波士顿动力公司(Boston Dynamics)与其仿人机器人 ATLAS HD 说再见了。这家机器人公司表示,现在是 ATLAS 退休 "休息放松 "的时候了,新的全电动 ATLAS 将接替它的工作。分享这段视频是为了纪念 ATLAS HD 的伟大时刻和那些不那么伟大的时刻。

 

标题横幅:AZT 是齐多夫定的研发名称,是第一种用于治疗艾滋病的药物。它被用于大剂量和单一疗法,造成了可怕的副作用和艾滋病病毒的抗药性。在随后 30 年的临床试验中,开发出了单片、每日一次、副作用有限的艾滋病治疗方案。现在,人们可以服用一种名为特鲁瓦达(Truvada)的双药组合来预防感染艾滋病毒的风险(如 DarkDrug 徽标所示)。

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