“Medicine is the restoration of discordant elements; sickness is the discord of the elements infused into the living body.” - Leonardo da Vinci

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Paint it yellow for the real world

There is a current trend to generate real-world data on medicines. This desire is being fuelled both by pharmaceutical companies and healthcare providers. In a cash restricted healthcare environment, those reimbursing new drugs want to know that they are getting value...

Prescribing on your gut?

On June 30th, the UK will wake up to another new world, probably less seismic than the EU referendum result, but one that will cause waves. In a drive for transparency and openness, the association of the British pharmaceutical industry (ABPI) will publish the amounts...

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  • Better chemo drug adsorption onto targeted...
    on September, 2018 at 3:08 pm

    One of the challenges in cancer research is improving the delivery of chemo drugs to enhance their efficacy while decreasing the risk of side effects. Scientists now perform a theoretical prediction of adsorption of a well-known chemo drug onto active carbon with aluminium inclusions, to show its […]

  • Drugs that stop mosquitoes catching malaria could...
    on September, 2018 at 12:20 pm

    Researchers have identified compounds that could prevent malaria parasites from being able to infect mosquitoes, halting the spread of disease. […]

  • E. coli's adaptation to extreme temperatures...
    on September, 2018 at 11:18 pm

    A new study suggests that defenses against extreme temperatures give E. coli bacteria an advantage in fending off certain drugs. The work could help doctors administer antibiotics in a more precise way. […]

  • Why some tuberculosis bacteria prove deadly
    on September, 2018 at 3:16 pm

    A new study has found that the same mutation that gives tuberculosis bacteria drug resistance also elicits a different -- and potentially weaker -- immune response. […]

  • Dietary fiber reduces brain inflammation during...
    on September, 2018 at 12:48 pm

    As mammals age, immune cells in the brain known as microglia become chronically inflamed. In this state, they produce chemicals known to impair cognitive and motor function. That's one explanation for why memory fades and other brain functions decline during old age. But, according to a new study, […]

  • Cancer drug and antidepressants provide clues for...
    on September, 2018 at 6:33 pm

    Researchers have now identified three new molecular drug targets in Naegleria fowleri and a number of drugs that are able to inhibit the amoeba's growth in a laboratory dish. Several of these drugs are already approved by the US Food and Drug Administration for other uses, such as antifungal […]

Header Banner: AZT the development name for zidovudine was the first drug launched to treat HIV. It was used in high doses and as monotherapy, causing horrendous side effects and resistance in the HIV virus. In the subsequent 30 years clinical trials has led to the development of single tablet, once daily regimens to treat HIV with limited side effects. Now a two pill combination called Truvada can be given to individuals to prevent the risk of acquiring HIV (shown in the DarkDrug logo).

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