“Medicine is the restoration of discordant elements; sickness is the discord of the elements infused into the living body.” - Leonardo da Vinci

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Paint it yellow for the real world

"Many HCPs do not realise that a medicine’s lack of effectiveness is reportable." There is a current trend to generate real-world data on medicines. This desire is being fuelled both by pharmaceutical companies and healthcare providers. In a cash...

Prescribing on your gut?

"It is unfair to disregard this association as an aberrant finding" On June 30th, the UK will wake up to another new world, probably less seismic than the EU referendum result, but one that will cause waves. In a drive for transparency and openness, the...

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  • Cancer device created to see if targeted...
    on July, 2019 at 7:00 pm

    Researchers have created a device that can determine whether targeted chemotherapy drugs are working on individual cancer patients. The portable device, which uses artificial intelligence and biosensors, is up to 95.9% accurate in counting live cancer cells when they pass through electrodes, […]

  • Turbo chip for drug development
    on July, 2019 at 2:52 pm

    In spite of increasing demand, the number of newly developed drugs decreased continuously in the past decades. The search for new active substances, their production, characterization, and screening for biological effectiveness are very complex and costly. One of the reasons is that all three steps […]

  • Pairing targeted drugs for breast and lung cancer...
    on July, 2019 at 12:06 am

    Targeted drugs for breast and lung cancer could be used together to overcome resistance to treatment in several different tumour types, a new study shows. Scientists discovered that when the breast cancer drug palbociclib was combined with the lung cancer drug crizotinib, the two-drug combination […]

  • No evidence of added benefit for most new drugs...
    on July, 2019 at 9:11 pm

    More than half of new drugs entering the German healthcare system have not been shown to add benefit, argue researchers. […]

  • Immune system effectiveness appears key to...
    on July, 2019 at 6:13 pm

    Mathematical modeling suggests that the rate at which a patient's immune system clears slow-growing variants of methicillin-resistant Staphylococcus aureus (MRSA) bacteria is a key determinant of whether antibiotics can cure the infection. […]

  • Anaphylactic shock: IgG antibodies and...
    on July, 2019 at 8:08 pm

    Teams have successfully identified a new pathological mechanism responsible for the unexplained cases of anaphylactic shock, involving neutrophils activated by antibodies of the IgG class. These findings will help improve diagnosis and treatment for patients with this type of shock. […]

Header Banner: AZT the development name for zidovudine was the first drug launched to treat HIV. It was used in high doses and as monotherapy, causing horrendous side effects and resistance in the HIV virus. In the subsequent 30 years clinical trials has led to the development of single tablet, once daily regimens to treat HIV with limited side effects. Now a two pill combination called Truvada can be given to individuals to prevent the risk of acquiring HIV (shown in the DarkDrug logo).

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