"Curiosity Killed the Cat"

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Revolutionizing Antivenom: The Quest to Neutralize Snake Venom with De Novo AI Designed Proteins

Snakebite envenoming poses a persistent threat to public health. The World Health Organization recognizes it as a neglected tropical disease, responsible for over 100,000 deaths annually and leaving another 300,000 individuals with permanent disabilities.In groundbreaking research, scientists have turned to de novo designed proteins as a novel approach to counteract these venom toxins. Using deep learning methods, researchers have successfully created protein designs that demonstrate potential as next-generation antivenom therapeutics.

Targeting Cellular Senescence: A New Frontier in Combating Cancer and Age-Related Diseases

In the realm of cellular biology, senescence has emerged as a pivotal process influencing both the progression of cancer and the onset of age-related diseases. Defined as a state where cells cease to divide but remain metabolically active, senescence acts as a double-edged sword. Key life sciences companies are pinning pipeline hopes in cracking this.

Hydroclimate Volatility: Navigating Extremes on a Warming Earth

In the face of a rapidly changing climate, the concept of hydroclimate volatility has emerged as a critical area of study, highlighting the dramatic and often sudden fluctuations between extremely dry and wet conditions. This phenomenon poses significant challenges to both natural ecosystems and human societies

Navigating the New Frontier: The First Abridged Complaint under the 2024 ABPI Code

In the ever-evolving landscape of pharmaceutical marketing, the industry faces a delicate balance between informing the public and adhering to strict regulations. This challenge was thrust into the spotlight with the recent case of CSL Seqirus and the alleged promotion of their prescription-only Flucelvax Influenza vaccine on the social media platform LinkedIn.

Dear World Leaders, A Clarion Call to Action: Addressing the Peril of Antarctic Sea Ice Loss

We write to you today with a profound sense of alarm and a pressing need for urgent action. The events unfolding in the Antarctic are a stark harbinger of the dangers posed by climate change, and they demand an immediate and concerted global response.

PHARMA

PharmaScience
Targeting Cellular Senescence: A New Frontier in Combating Cancer and Age-Related Diseases

Targeting Cellular Senescence: A New Frontier in Combating Cancer and Age-Related Diseases

In the realm of cellular biology, senescence has emerged as a pivotal process influencing both the progression of cancer and the onset of age-related diseases. Defined as a state where cells cease to divide but remain metabolically active, senescence acts as a double-edged sword. Key life sciences companies are pinning pipeline hopes in cracking this.

Pharma

Navigating the New Frontier: The First Abridged Complaint under the 2024 ABPI Code

In the ever-evolving landscape of pharmaceutical marketing, the industry faces a delicate balance between informing the public and adhering to strict regulations. This challenge was thrust into the spotlight with the recent case of CSL Seqirus and the alleged promotion of their prescription-only Flucelvax Influenza vaccine on the social media platform LinkedIn.

AIPharmaScience

Stability Oracle: A Powerful Tool for Engineering Stable Proteins

In the rapidly evolving world of biotechnology, the ability to engineer proteins with enhanced stability is a critical challenge. Computational methods that can accurately predict how amino acid mutations will impact a protein's thermodynamic stability could revolutionize the protein engineering process. Enter Stability Oracle, a new deep learning framework that outperforms state-of-the-art methods in predicting thermodynamically stabilizing protein mutations

Pharma

A New Era in US Schizophrenia Treatment: The FDA Approval of COBENFY

In a significant development for the field of neuropsychiatry, the U.S. Food and Drug Administration (FDA) has granted approval for COBENFY™ (xanomeline and trospium chloride), marking the introduction of the first new pharmacological approach to treating schizophrenia in decades

HEALTH

EditorialHealth
Unveiling Injustice: The Imperative of Addressing Racism in Global Child Health

Unveiling Injustice: The Imperative of Addressing Racism in Global Child Health

The recently launched Lancet Commission on Racism and Child Health has embarked on a pioneering journey to unravel the profound impact of racism, xenophobia, and discrimination on child health worldwide. This editorial delves into the multifaceted dimensions of this issue, exploring the pathways through which racism affects health outcomes and highlighting the urgent need for systemic change.

Health
Rethinking Suicide Prevention: A Public Health Approach to a Global Problem

Rethinking Suicide Prevention: A Public Health Approach to a Global Problem

Suicide is a major public health crisis, claiming over 700,000 lives globally each year. Yet, despite its staggering toll, suicide is a preventable tragedy. A new framework is emerging that could transform how we approach this complex issue - by shifting the focus from individual-level risk factors to the broader social determinants that shape suicide risk across populations

HealthScience
Outwitting the Fungal Invaders: How Pathogens Hijack Our Immune Defenses

Outwitting the Fungal Invaders: How Pathogens Hijack Our Immune Defenses

Fungi are often overlooked as a major threat to human health, overshadowed by the more dramatic impacts of bacterial and viral infections. Yet these eukaryotic microbes pose a serious and growing danger, responsible for millions of deaths worldwide each year. And their success is largely due to their ability to manipulate the very immune defenses we rely on to keep us healthy.

SCIENCE, TECHNOLOGY

PharmaScience
Targeting Cellular Senescence: A New Frontier in Combating Cancer and Age-Related Diseases

Targeting Cellular Senescence: A New Frontier in Combating Cancer and Age-Related Diseases

In the realm of cellular biology, senescence has emerged as a pivotal process influencing both the progression of cancer and the onset of age-related diseases. Defined as a state where cells cease to divide but remain metabolically active, senescence acts as a double-edged sword. Key life sciences companies are pinning pipeline hopes in cracking this.

EditorialScience
The Connectome Conquest: Mapping the Brain’s Secrets

The Connectome Conquest: Mapping the Brain’s Secrets

Seung and Murthy have been developing the FlyWire map for more than four years, using electron microscopy images of slices of the fly’s brain. The researchers and their hundreds of global colleagues stitched the data together to form a full map of the brain with the help of artificial-intelligence (AI) tools. This is an immense achievement and already is revolutionising the field.

AIPharmaScience
Stability Oracle: A Powerful Tool for Engineering Stable Proteins

Stability Oracle: A Powerful Tool for Engineering Stable Proteins

In the rapidly evolving world of biotechnology, the ability to engineer proteins with enhanced stability is a critical challenge. Computational methods that can accurately predict how amino acid mutations will impact a protein's thermodynamic stability could revolutionize the protein engineering process. Enter Stability Oracle, a new deep learning framework that outperforms state-of-the-art methods in predicting thermodynamically stabilizing protein mutations

HealthScience
Outwitting the Fungal Invaders: How Pathogens Hijack Our Immune Defenses

Outwitting the Fungal Invaders: How Pathogens Hijack Our Immune Defenses

Fungi are often overlooked as a major threat to human health, overshadowed by the more dramatic impacts of bacterial and viral infections. Yet these eukaryotic microbes pose a serious and growing danger, responsible for millions of deaths worldwide each year. And their success is largely due to their ability to manipulate the very immune defenses we rely on to keep us healthy.

Science
Quenching the Thirst of the Arid World: Compact Fuel-Powered Atmospheric Water Harvesters

Quenching the Thirst of the Arid World: Compact Fuel-Powered Atmospheric Water Harvesters

As the global population continues to surge and climate change disrupts traditional water sources, the need for innovative approaches to freshwater production has never been more pressing. Now a promising solution has emerged in the form of sorption-based atmospheric water harvesting (SAWH) devices

EDITORIAL

Dear World Leaders, A Clarion Call to Action: Addressing the Peril of Antarctic Sea Ice Loss

We write to you today with a profound sense of alarm and a pressing need for urgent action. The events unfolding in the Antarctic are a stark harbinger of the dangers posed by climate change, and they demand an immediate and concerted global response.

GO EXPLORING

ACTIVITY

ACTIVITY | Unraveling the Marvels of the Twist Museum in London

Nestled in the heart of London, the Twist Museum stands as a remarkable testament to the art of the unexpected. With its captivating exhibits and thought-provoking installations, this hidden gem offers visitors a unique and memorable experience like no other

ACTIVITY

ACTIVITY | The Lyrid Meteor Shower: An April Sky Spectacle

In the vast expanse of the night sky, a captivating celestial event awaits astronomy enthusiasts and stargazers alike. Brace yourselves for the Lyrid meteor shower, a dazzling display of shooting stars that occurs annually in mid to late April.

ACTIVITY
ACTIVITY | The Great Exhibition Road Festival: A Celebration of Science, Art, and Innovation

ACTIVITY | The Great Exhibition Road Festival: A Celebration of Science, Art, and Innovation

The Great Exhibition Road Festival is a free annual celebration of science and the arts each summer in South Kensington. Join us in June 2024 for a weekend of free science and arts events for all ages. Enjoy hands-on workshops, fascinating talks, performances and installations from iconic museums, research and culture organisations

ACTIVITY
ACTIVITY | Exploring Wonder and Discovery: A Journey Through the Science and Industry Museum in Manchester

ACTIVITY | Exploring Wonder and Discovery: A Journey Through the Science and Industry Museum in Manchester

The Science and Industry Museum in Manchester is a captivating destination that offers a wide array of exhibits and activities for both children and adults. With its commitment to fostering curiosity, innovation, and learning, the museum stands as a gateway to the wonders of science and the marvels of industrial history

ACTIVITY
ACTIVITY | Exploring the Wonders of Kew Gardens: A Paradise for Young Explorers

ACTIVITY | Exploring the Wonders of Kew Gardens: A Paradise for Young Explorers

Nestled in the heart of London, Kew Gardens is a remarkable botanical paradise that captivates visitors of all ages. While its beauty and scientific significance are widely acclaimed, Kew Gardens holds a special allure for children, offering a myriad of exciting activities and educational opportunities

BBC Virtual Reality Rome

This website has now closed, we are seraching frantically for a similar experience!

Hubble Organisation

Since it launch on the Spacce Shuttle Discovery on On April 24, 1990, Hubble has revealed properties of space and time that for most of human history were only probed in the imaginations of scientists and philosophers.

Sense About Science

Sense about Science is an independent charity that promotes the public interest in sound science and evidence. Founded in 2002, Sense about Science works with decision-makers, world-leading researchers and community groups to raise the standard of evidence in public life.

Chandra Observatory

Since its launch on July 23, 1999, the Chandra X-ray Observatory has been NASA’s flagship mission for X-ray astronomy, taking its place in the fleet of “Great Observatories.”

The IUCN Red List

Established in 1964, the International Union for Conservation of Nature’s Red List of Threatened Species has evolved to become the world’s most comprehensive information source on the global extinction risk status of animal, fungus and plant species.

Scott Hartman's Skeletal Drawings

Scott Hartman’s detailed and rigorous skeletal reconstructions set the standard for sauropods: he’s now become the first port of call when looking for precise, anatomically correct work.

FlyWire is a human-AI collaboration for reconstructing the full brain connectome of Drosophila. It is made possible by contributions from hundreds of scientists around the globe. The potential benefits of such a resource are immense – we can now make significant advances in our understanding of how the brain works by ultimately linking neuronal wiring with brain function.

 

Science

  • Strong as steel, light as foam: High-performance,...
    on January, 2025 at 8:42 pm

    Researchers have used machine learning to design nano-architected materials that have the strength of carbon steel but the lightness of Styrofoam. The team describes how they made nanomaterials with properties that offer a conflicting combination of exceptional strength, light weight and […]

Technology

  • Strong as steel, light as foam: High-performance,...
    on January, 2025 at 8:42 pm

    Researchers have used machine learning to design nano-architected materials that have the strength of carbon steel but the lightness of Styrofoam. The team describes how they made nanomaterials with properties that offer a conflicting combination of exceptional strength, light weight and […]

Pharma

  • Scientists design peptides to enhance drug...
    on January, 2025 at 9:51 pm

    Scientists have developed a groundbreaking approach using specially designed peptides to improve drug formulations. This innovative method significantly enhances anti-tumor efficacy.

Health

  • Combination of dual-targeted therapies and...
    on January, 2025 at 8:27 pm

    Patients with metastatic colorectal cancer (mCRC) harboring BRAF V600E mutations benefited from first-line treatment with the targeted therapies encorafenib and cetuximab plus a mFOLFOX6 chemotherapy regimen, according to results from the PhaseIII BREAKWATER trial.

HEADER IMAGE | A solitary boy sits amidst urban destruction as monstrous storms wreak havoc in a nightmarish scene brought on by the relentless rise in global temperatures. Are we being over dramatic? We think not. The time to be polite regarding the topic has passed. ADOBE STOCK #1068157517

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