Science

“Two things are infinite: the universe and human stupidity; and I'm not sure about the universe.” ― Albert Einstein

Science

Revolutionizing Antivenom: The Quest to Neutralize Snake Venom with De Novo AI Designed Proteins

Revolutionizing Antivenom: The Quest to Neutralize Snake Venom with De Novo AI Designed Proteins

Snakebite envenoming poses a persistent threat to public health. The World Health Organization recognizes it as a neglected tropical disease, responsible for over 100,000 deaths annually and leaving another 300,000 individuals with permanent disabilities.In groundbreaking research, scientists have turned to de novo designed proteins as a novel approach to counteract these venom toxins. Using deep learning methods, researchers have successfully created protein designs that demonstrate potential as next-generation antivenom therapeutics.

AIScience
Revolutionizing Antivenom: The Quest to Neutralize Snake Venom with De Novo AI Designed Proteins

Revolutionizing Antivenom: The Quest to Neutralize Snake Venom with De Novo AI Designed Proteins

Snakebite envenoming poses a persistent threat to public health. The World Health Organization recognizes it as a neglected tropical disease, responsible for over 100,000 deaths annually and leaving another 300,000 individuals with permanent disabilities.In groundbreaking research, scientists have turned to de novo designed proteins as a novel approach to counteract these venom toxins. Using deep learning methods, researchers have successfully created protein designs that demonstrate potential as next-generation antivenom therapeutics.

PharmaScience
Targeting Cellular Senescence: A New Frontier in Combating Cancer and Age-Related Diseases

Targeting Cellular Senescence: A New Frontier in Combating Cancer and Age-Related Diseases

In the realm of cellular biology, senescence has emerged as a pivotal process influencing both the progression of cancer and the onset of age-related diseases. Defined as a state where cells cease to divide but remain metabolically active, senescence acts as a double-edged sword. Key life sciences companies are pinning pipeline hopes in cracking this.

EditorialScience
The Connectome Conquest: Mapping the Brain’s Secrets

The Connectome Conquest: Mapping the Brain’s Secrets

Seung and Murthy have been developing the FlyWire map for more than four years, using electron microscopy images of slices of the fly’s brain. The researchers and their hundreds of global colleagues stitched the data together to form a full map of the brain with the help of artificial-intelligence (AI) tools. This is an immense achievement and already is revolutionising the field.

AIPharmaScience
Stability Oracle: A Powerful Tool for Engineering Stable Proteins

Stability Oracle: A Powerful Tool for Engineering Stable Proteins

In the rapidly evolving world of biotechnology, the ability to engineer proteins with enhanced stability is a critical challenge. Computational methods that can accurately predict how amino acid mutations will impact a protein's thermodynamic stability could revolutionize the protein engineering process. Enter Stability Oracle, a new deep learning framework that outperforms state-of-the-art methods in predicting thermodynamically stabilizing protein mutations

HealthScience
Outwitting the Fungal Invaders: How Pathogens Hijack Our Immune Defenses

Outwitting the Fungal Invaders: How Pathogens Hijack Our Immune Defenses

Fungi are often overlooked as a major threat to human health, overshadowed by the more dramatic impacts of bacterial and viral infections. Yet these eukaryotic microbes pose a serious and growing danger, responsible for millions of deaths worldwide each year. And their success is largely due to their ability to manipulate the very immune defenses we rely on to keep us healthy.

Science
Quenching the Thirst of the Arid World: Compact Fuel-Powered Atmospheric Water Harvesters

Quenching the Thirst of the Arid World: Compact Fuel-Powered Atmospheric Water Harvesters

As the global population continues to surge and climate change disrupts traditional water sources, the need for innovative approaches to freshwater production has never been more pressing. Now a promising solution has emerged in the form of sorption-based atmospheric water harvesting (SAWH) devices

  • Solar and electric-powered homes feel the effects...
    on February, 2025 at 11:19 pm

    An expert in energy technologies uses AI tools to investigate the impact of extreme weather on solar-powered and electrified homes and uncover their unique vulnerabilities and develop insights on how they handle harsh conditions.

  • Personalized cancer treatment using 3D...
    on February, 2025 at 5:27 pm

    Scientists have successfully developed a gastric cancer model using 3D bioprinting technology and patient-derived cancer tissue fragments. This innovative model preserves the characteristics of actual patient tissues and is expected to rapidly evaluate and predict individual patient drug responses.

  • Temperamental stars are distorting our view of...
    on February, 2025 at 5:24 pm

    'Temperamental' stars that brighten and dim over a matter of hours or days may be distorting our view of thousands of distant planets, suggests a new study.

  • Researchers achieve total synthesis of ibogaine
    on February, 2025 at 3:39 am

    Researchers have achieved total chemical synthesis of the psychoactive compound ibogaine and its analogs from pyridine. The discovery will make it easier to explore the therapeutic possibilities of ibogaine.

  • Multinational research project shows how life on...
    on February, 2025 at 9:47 pm

    Measurements and data collected from space can be used to better understand life on Earth. An ambitious, multinational research project has demonstrated that Earth's biodiversity can be monitored and measured from space, leading to a better understanding of terrestrial and aquatic ecosystems.

BBC Virtual Reality Rome

This website has now closed, we are seraching frantically for a similar experience!

Hubble Organisation

Since it launch on the Spacce Shuttle Discovery on On April 24, 1990, Hubble has revealed properties of space and time that for most of human history were only probed in the imaginations of scientists and philosophers. 

Sense About Science

Sense about Science is an independent charity that promotes the public interest in sound science and evidence. Founded in 2002, Sense about Science works with decision-makers, world-leading researchers and community groups to raise the standard of evidence in public life.

Chandra Observatory

Since its launch on July 23, 1999, the Chandra X-ray Observatory has been NASA’s flagship mission for X-ray astronomy, taking its place in the fleet of “Great Observatories.”

The IUCN Red List

Established in 1964, the International Union for Conservation of Nature’s Red List of Threatened Species has evolved to become the world’s most comprehensive information source on the global extinction risk status of animal, fungus and plant species.

Scott Hartman's Skeletal Drawings

Scott Hartman’s detailed and rigorous skeletal reconstructions set the standard for sauropods: he’s now become the first port of call when looking for precise, anatomically correct work.

After 11 years, Boston Dynamics has said goodbye to its humanoid robot ATLAS HD. The robotics company says it’s time for ATLAS to “kick back and relax” in retirement, letting the new all electric ATLAS take over. This video was shared to remember ATLAS HD’s great moments and those not so great.

 

Header Banner: On 4 July 2012, the ATLAS and CMS experiments at CERN’s Large Hadron Collider announced they had each observed a new particle in the mass region around 126 GeV. This particle is consistent with the Higgs boson predicted by the Standard Model. The Higgs boson, as proposed within the Standard Model, is the simplest manifestation of the Brout-Englert-Higgs mechanism. Other types of Higgs bosons are predicted by other theories that go beyond the Standard Model. On 8 October 2013 the Nobel prize in physics (link is external) was awarded jointly to François Englert and Peter Higgs “for the theoretical discovery of a mechanism that contributes to our understanding of the origin of mass of subatomic particles, and which recently was confirmed through the discovery of the predicted fundamental particle, by the ATLAS and CMS experiments at CERN’s Large Hadron Collider”. The DarkDrug logo shows the Milky Way, the galaxy we call home and yet only explored a fraction of.

Pin It on Pinterest

DarkDrug

FREE
VIEW