BIOLOGY

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BIOLOGY

Stability Oracle: A Powerful Tool for Engineering Stable Proteins

Stability Oracle: A Powerful Tool for Engineering Stable Proteins

In the rapidly evolving world of biotechnology, the ability to engineer proteins with enhanced stability is a critical challenge. Computational methods that can accurately predict how amino acid mutations will impact a protein’s thermodynamic stability could revolutionize the protein engineering process. Enter Stability Oracle, a new deep learning framework that outperforms state-of-the-art methods in predicting thermodynamically stabilizing protein mutations

AIPharmaScience
Stability Oracle: A Powerful Tool for Engineering Stable Proteins

Stability Oracle: A Powerful Tool for Engineering Stable Proteins

In the rapidly evolving world of biotechnology, the ability to engineer proteins with enhanced stability is a critical challenge. Computational methods that can accurately predict how amino acid mutations will impact a protein's thermodynamic stability could revolutionize the protein engineering process. Enter Stability Oracle, a new deep learning framework that outperforms state-of-the-art methods in predicting thermodynamically stabilizing protein mutations

  • NASA's Hubble, Webb probe surprisingly smooth...
    on November, 2024 at 4:35 pm

    Teams of astronomers used the combined power of NASA's Hubble and James Webb space telescopes to revisit the legendary Vega disk.

  • Autistic traits shape how we explore
    on October, 2024 at 7:18 pm

    People with stronger autistic trails showed distinct exploration patterns and higher levels of persistence in a computer game, ultimately resulting in better performance than people with lower scores of autistic traits, according to a new study.

  • Violating Bredt's rule: Chemists just broke a...
    on October, 2024 at 7:18 pm

    According to Bredt's rule, double bonds cannot exist at certain positions on organic molecules if the molecule's geometry deviates too far from what we learn in textbooks. This rule has constrained chemists for a century. Chemists have now shown how to make molecules that violate Bredt's rule, […]

  • New methods for whale tracking and rendezvous...
    on October, 2024 at 7:17 pm

    Today, a research team has proposed a new reinforcement learning framework with autonomous drones to find sperm whales and predict where they will surface.

  • Immune system review provides insight into more...
    on October, 2024 at 7:17 pm

    As critical responders, macrophages can perceive helpful biotechnology as threats. If not created with the right materials or mechanical forces, these devices can trigger an immune response that can cause inflammation, scar tissue or device failure.

BBC Virtual Reality Rome

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Hubble Organisation

Since it launch on the Spacce Shuttle Discovery on On April 24, 1990, Hubble has revealed properties of space and time that for most of human history were only probed in the imaginations of scientists and philosophers. 

Sense About Science

Sense about Science is an independent charity that promotes the public interest in sound science and evidence. Founded in 2002, Sense about Science works with decision-makers, world-leading researchers and community groups to raise the standard of evidence in public life.

Chandra Observatory

Since its launch on July 23, 1999, the Chandra X-ray Observatory has been NASA’s flagship mission for X-ray astronomy, taking its place in the fleet of “Great Observatories.”

The IUCN Red List

Established in 1964, the International Union for Conservation of Nature’s Red List of Threatened Species has evolved to become the world’s most comprehensive information source on the global extinction risk status of animal, fungus and plant species.

Scott Hartman's Skeletal Drawings

Scott Hartman’s detailed and rigorous skeletal reconstructions set the standard for sauropods: he’s now become the first port of call when looking for precise, anatomically correct work.

After 11 years, Boston Dynamics has said goodbye to its humanoid robot ATLAS HD. The robotics company says it’s time for ATLAS to “kick back and relax” in retirement, letting the new all electric ATLAS take over. This video was shared to remember ATLAS HD’s great moments and those not so great.

 

Header Banner: Speed is the name of the game. The DarkDrug logo shows an Intel Xeon microchip die. Xeon is a brand of x86 microprocessors designed, manufactured, and marketed by Intel, targeted at the non-consumer workstation, server, and embedded system markets. It was introduced in June 1998. The advent ofoptical fibre cable has allowed the speed of data transmission to reach dizzy heights (shown in the DarkDrug logo). The field of applied science and engineering concerned with the design and application of optical fibers is known as fibre optics. The term was coined by Indian physicist Narinder Singh Kapany, who is widely acknowledged as the father of fibre optics.

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