Dilruwan Herath

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Revolutionizing Antivenom: The Quest to Neutralize Snake Venom with De Novo AI Designed Proteins

Revolutionizing Antivenom: The Quest to Neutralize Snake Venom with De Novo AI Designed Proteins

Snakebite envenoming poses a persistent threat to public health. The World Health Organization recognizes it as a neglected tropical disease, responsible for over 100,000 deaths annually and leaving another 300,000 individuals with permanent disabilities.In groundbreaking research, scientists have turned to de novo designed proteins as a novel approach to counteract these venom toxins. Using deep learning methods, researchers have successfully created protein designs that demonstrate potential as next-generation antivenom therapeutics.

AIScience
Revolutionizing Antivenom: The Quest to Neutralize Snake Venom with De Novo AI Designed Proteins

Revolutionizing Antivenom: The Quest to Neutralize Snake Venom with De Novo AI Designed Proteins

Snakebite envenoming poses a persistent threat to public health. The World Health Organization recognizes it as a neglected tropical disease, responsible for over 100,000 deaths annually and leaving another 300,000 individuals with permanent disabilities.In groundbreaking research, scientists have turned to de novo designed proteins as a novel approach to counteract these venom toxins. Using deep learning methods, researchers have successfully created protein designs that demonstrate potential as next-generation antivenom therapeutics.

PharmaScience
Targeting Cellular Senescence: A New Frontier in Combating Cancer and Age-Related Diseases

Targeting Cellular Senescence: A New Frontier in Combating Cancer and Age-Related Diseases

In the realm of cellular biology, senescence has emerged as a pivotal process influencing both the progression of cancer and the onset of age-related diseases. Defined as a state where cells cease to divide but remain metabolically active, senescence acts as a double-edged sword. Key life sciences companies are pinning pipeline hopes in cracking this.

Pharma
Navigating the New Frontier: The First Abridged Complaint under the 2024 ABPI Code

Navigating the New Frontier: The First Abridged Complaint under the 2024 ABPI Code

In the ever-evolving landscape of pharmaceutical marketing, the industry faces a delicate balance between informing the public and adhering to strict regulations. This challenge was thrust into the spotlight with the recent case of CSL Seqirus and the alleged promotion of their prescription-only Flucelvax Influenza vaccine on the social media platform LinkedIn.

EditorialHealth
Unveiling Injustice: The Imperative of Addressing Racism in Global Child Health

Unveiling Injustice: The Imperative of Addressing Racism in Global Child Health

The recently launched Lancet Commission on Racism and Child Health has embarked on a pioneering journey to unravel the profound impact of racism, xenophobia, and discrimination on child health worldwide. This editorial delves into the multifaceted dimensions of this issue, exploring the pathways through which racism affects health outcomes and highlighting the urgent need for systemic change.

EditorialScience
The Connectome Conquest: Mapping the Brain’s Secrets

The Connectome Conquest: Mapping the Brain’s Secrets

Seung and Murthy have been developing the FlyWire map for more than four years, using electron microscopy images of slices of the fly’s brain. The researchers and their hundreds of global colleagues stitched the data together to form a full map of the brain with the help of artificial-intelligence (AI) tools. This is an immense achievement and already is revolutionising the field.

AIPharmaScience
Stability Oracle: A Powerful Tool for Engineering Stable Proteins

Stability Oracle: A Powerful Tool for Engineering Stable Proteins

In the rapidly evolving world of biotechnology, the ability to engineer proteins with enhanced stability is a critical challenge. Computational methods that can accurately predict how amino acid mutations will impact a protein's thermodynamic stability could revolutionize the protein engineering process. Enter Stability Oracle, a new deep learning framework that outperforms state-of-the-art methods in predicting thermodynamically stabilizing protein mutations

  • Millions of new solar system objects to be found...
    on June, 2025 at 1:34 am

    Astronomers have revealed new research showing that millions of new solar system objects are likely to be detected by a brand-new facility, which is expected to come online later this year.

  • Collaboration can unlock Australia's energy...
    on June, 2025 at 9:29 pm

    New research demonstrates that with collaboration between stakeholders, Australia can fully decarbonize its domestic and energy export economies by 2060 -- a feat requiring $6.2 trillion USD and around 110,000 square kilomters of land -- while avoiding harm to important areas for biodiversity […]

  • Guardrails, education urged to protect adolescent...
    on June, 2025 at 6:12 pm

    The effects of artificial intelligence on adolescents are nuanced and complex, according to a new report that calls on developers to prioritize features that protect young people from exploitation, manipulation and the erosion of real-world relationships.

  • Molecular link between air pollution and...
    on June, 2025 at 6:12 pm

    A new study found exposure to specific tiny particles in air pollution during pregnancy are associated with increased risk of various negative birth outcomes.

  • Atmospheric chemistry keeps pollutants in the air
    on June, 2025 at 3:50 pm

    A new study details processes that keep pollutants aloft despite a drop in emissions.

BBC Virtual Reality Rome

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Hubble Organisation

Since it launch on the Spacce Shuttle Discovery on On April 24, 1990, Hubble has revealed properties of space and time that for most of human history were only probed in the imaginations of scientists and philosophers. 

Sense About Science

Sense about Science is an independent charity that promotes the public interest in sound science and evidence. Founded in 2002, Sense about Science works with decision-makers, world-leading researchers and community groups to raise the standard of evidence in public life.

Chandra Observatory

Since its launch on July 23, 1999, the Chandra X-ray Observatory has been NASA’s flagship mission for X-ray astronomy, taking its place in the fleet of “Great Observatories.”

The IUCN Red List

Established in 1964, the International Union for Conservation of Nature’s Red List of Threatened Species has evolved to become the world’s most comprehensive information source on the global extinction risk status of animal, fungus and plant species.

Scott Hartman's Skeletal Drawings

Scott Hartman’s detailed and rigorous skeletal reconstructions set the standard for sauropods: he’s now become the first port of call when looking for precise, anatomically correct work.

After 11 years, Boston Dynamics has said goodbye to its humanoid robot ATLAS HD. The robotics company says it’s time for ATLAS to “kick back and relax” in retirement, letting the new all electric ATLAS take over. This video was shared to remember ATLAS HD’s great moments and those not so great.

 

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